7FU7

Crystal Structure of human cyclic GMP-AMP synthase

7FU7 の概要

• エントリーDOI: 10.2210/pdb7fu7/pdb
• Group deposition: To be published (G_1002263)
• 分子名称: Cyclic GMP-AMP synthase, ZINC ION, (6M)-2-(benzylamino)-6-(2-chloro-4-methylphenyl)-1H-benzimidazole-4-carboxylic acid, ... (4 entities in total)
• 機能のキーワード: nucleotidyltransferase, cyclic gmp-amp synthase, cgas, dna-binding, activator dna, pattern recognition receptor, innate immune response, viral dna recognition, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 42862.17

構造登録者

Leibrock, L.,Benz, J.,Groebke-Zbinden, K.,Rudolph, M.G. (登録日: 2023-02-08, 公開日: 2024-02-21)

• 主引用文献: Groebke-Zbinden, K.,Vandemeulebroucke, A.,Hilbert, M.,Rudolph, M.G.; Crystal Structure of a human cyclic GMP-AMP synthase complex; To be published,

実験手法

X-RAY DIFFRACTION (2.24 Å)