7FQJ
Crystal Structure of human Legumain in complex with (2S)-N-[(1S)-3-amino-1-cyano-3-oxopropyl]-1-[1-[4-[(2,4-difluorophenyl)methoxy]phenyl]cyclopropanecarbonyl]pyrrolidine-2-carboxamide
7FQJ の概要
エントリーDOI | 10.2210/pdb7fqj/pdb |
Group deposition | To be published (G_1002245) |
分子名称 | Legumain, SULFATE ION, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total) |
機能のキーワード | cysteine protease, allosteric inhibitor, asparaginyl endopeptidase, alzheimer's disease, hydrolase, hydrolase-inhibitor complex, hydrolase/inhibitor |
由来する生物種 | Homo sapiens (human) |
タンパク質・核酸の鎖数 | 3 |
化学式量合計 | 155985.67 |
構造登録者 | |
主引用文献 | Bartels, B.,Kuhn, B.,Benz, J.,Rudolph, M.G. Crystal Structure of a human Legumain complex To be published, |
実験手法 | X-RAY DIFFRACTION (1.7 Å) |
構造検証レポート
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