7FCQ

Crystallographic structure of neutralizing antibody P14-44 in complex with SARS-CoV-2 spike receptor-binding Domain (RBD)

7FCQ の概要

• エントリーDOI: 10.2210/pdb7fcq/pdb
• 分子名称: Spike protein S1, P14-44 antibody Fab fragment heavy chain, P14-44 antibody Fab fragment light chain, ... (6 entities in total)
• 機能のキーワード: sars-cov-2, rbd, neutralizing antibodies, antiviral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 71551.57

構造登録者

Zheng, P.,Jin, T. (登録日: 2021-07-15, 公開日: 2022-06-15, 最終更新日: 2023-11-29)

• 主引用文献: Zou, J.,Li, L.,Zheng, P.,Liang, W.,Hu, S.,Zhou, S.,Wang, Y.,Zhao, J.,Yuan, D.,Liu, L.,Wu, D.,Xu, M.,Zhang, F.,Zhu, M.,Wu, Z.,Cao, X.,Ni, M.,Ling, X.,Wu, Y.,Kuang, Z.,Hu, M.,Li, J.,Li, X.,Guo, X.,Xu, T.,Jiang, H.,Gao, C.,Yu, M.,Liu, J.,Zhong, N.,Zhou, J.,Huang, J.A.,Jin, T.,He, J.; Ultrapotent neutralizing antibodies against SARS-CoV-2 with a high degree of mutation resistance.; J.Clin.Invest., 132:-, 2022; PubMed: 35108220; DOI: 10.1172/JCI154987

実験手法

X-RAY DIFFRACTION (1.89 Å)