7FCI
human NTCP in complex with YN69083 Fab
Summary for 7FCI
Entry DOI | 10.2210/pdb7fci/pdb |
EMDB information | 31526 |
Descriptor | Sodium/bile acid cotransporter, Fab Light chain, Fab Heavy chain (3 entities in total) |
Functional Keywords | transporter, transport protein, transport protein-immune system complex, transport protein/immune system |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 89330.38 |
Authors | Park, J.H.,Iwamoto, M.,Yun, J.H.,Uchikubo-Kamo, T.,Son, D.,Jin, Z.,Yoshida, H.,Ohki, M.,Ishimoto, N.,Mizutani, K.,Oshima, M.,Muramatsu, M.,Wakita, T.,Shirouzu, M.,Liu, K.,Uemura, T.,Nomura, N.,Iwata, S.,Watashi, K.,Tame, J.R.H.,Nishizawa, T.,Lee, W.,Park, S.Y. (deposition date: 2021-07-14, release date: 2022-05-25, Last modification date: 2022-07-13) |
Primary citation | Park, J.H.,Iwamoto, M.,Yun, J.H.,Uchikubo-Kamo, T.,Son, D.,Jin, Z.,Yoshida, H.,Ohki, M.,Ishimoto, N.,Mizutani, K.,Oshima, M.,Muramatsu, M.,Wakita, T.,Shirouzu, M.,Liu, K.,Uemura, T.,Nomura, N.,Iwata, S.,Watashi, K.,Tame, J.R.H.,Nishizawa, T.,Lee, W.,Park, S.Y. Structural insights into the HBV receptor and bile acid transporter NTCP. Nature, 606:1027-1031, 2022 Cited by PubMed: 35580630DOI: 10.1038/s41586-022-04857-0 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.3 Å) |
Structure validation
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