7F9W
CD25 in complex with Fab
Summary for 7F9W
Entry DOI | 10.2210/pdb7f9w/pdb |
EMDB information | 31499 |
Descriptor | Interleukin-2 receptor subunit alpha, Light chain of Fab, Heavy chain of Fab (3 entities in total) |
Functional Keywords | cd25, antibody, il-2, antitumor protein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 92184.34 |
Authors | |
Primary citation | Song, D.,Liu, X.,Dong, C.,Wang, Q.,Sha, C.,Liu, C.,Ning, Z.,Han, J.,Liu, H.,Zong, M.,Zhao, Y.,Li, Y.,Liu, G.,Shao, X.,Dou, C. Two novel human anti-CD25 antibodies with antitumor activity inversely related to their affinity and in vitro activity. Sci Rep, 11:22966-22966, 2021 Cited by PubMed: 34824364DOI: 10.1038/s41598-021-02449-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
Download full validation report