7F96

Plasmodium falciparum Prolyl-tRNA Synthetase (PfPRS) in Complex with L-proline and compound L95

Summary for 7F96

• Entry DOI: 10.2210/pdb7f96/pdb
• Descriptor: Proline--tRNA ligase, ~{N}-[4-[(3~{S})-3-cyano-3-cyclopropyl-2-oxidanylidene-pyrrolidin-1-yl]-6-methyl-pyridin-2-yl]-2-phenyl-ethanamide, PROLINE, ... (4 entities in total)
• Functional Keywords: protein translation, malaria, inhibitor, prs, ligase
• Biological source: Plasmodium falciparum 3D7
• Total number of polymer chains: 1
• Total formula weight: 58290.75

Authors

Mishra, S.,Malhotra, N.,Manickam, Y.,Sharma, A. (deposition date: 2021-07-04, release date: 2023-01-04, Last modification date: 2024-05-29)

• Primary citation: Mishra, S.,Malhotra, N.,Manickam, Y.,Sharma, A.; PfPRS with ATP binding pocket inhibitor; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.577 Å)