7F94
Structure of C-terminal truncated connexin43/Cx43/GJA1 gap junction intercellular channel with two conformationally different hemichannels
Summary for 7F94
Entry DOI | 10.2210/pdb7f94/pdb |
EMDB information | 31497 |
Descriptor | A C-terminal deletion mutant of gap junction alpha-1 protein (Cx43-M257) (1 entity in total) |
Functional Keywords | cx43, connexin, gap junction channel, gating mechanism, membrane protein |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 12 |
Total formula weight | 352758.56 |
Authors | |
Primary citation | Lee, H.J.,Cha, H.J.,Jeong, H.,Lee, S.N.,Lee, C.W.,Kim, M.,Yoo, J.,Woo, J.S. Conformational changes in the human Cx43/GJA1 gap junction channel visualized using cryo-EM. Nat Commun, 14:931-931, 2023 Cited by PubMed: 36805660DOI: 10.1038/s41467-023-36593-y PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.6 Å) |
Structure validation
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