7F8W

Cryo-EM structure of the cholecystokinin receptor CCKBR in complex with gastrin-17 and Gq

7F8W の概要

• エントリーDOI: 10.2210/pdb7f8w/pdb
• EMDBエントリー: 31493 31494
• 分子名称: Guanine nucleotide-binding protein G(q) subunit alpha, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
• 機能のキーワード: g protein-coulped receptor, cholecystokinin receptor cckbr, gastrin-17, structural protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 169202.86

構造登録者

Zhang, X.,He, C.,Wang, M.,Zhou, Q.,Yang, D.,Zhu, Y.,Wu, B.,Zhao, Q. (登録日: 2021-07-02, 公開日: 2021-10-13, 最終更新日: 2022-02-16)

• 主引用文献: Zhang, X.,He, C.,Wang, M.,Zhou, Q.,Yang, D.,Zhu, Y.,Feng, W.,Zhang, H.,Dai, A.,Chu, X.,Wang, J.,Yang, Z.,Jiang, Y.,Sensfuss, U.,Tan, Q.,Han, S.,Reedtz-Runge, S.,Xu, H.E.,Zhao, S.,Wang, M.W.,Wu, B.,Zhao, Q.; Structures of the human cholecystokinin receptors bound to agonists and antagonists.; Nat.Chem.Biol., 17:1230-1237, 2021; PubMed: 34556863; DOI: 10.1038/s41589-021-00866-8

実験手法

ELECTRON MICROSCOPY (3.1 Å)