7F8U

Crystal structure of the cholecystokinin receptor CCKAR in complex with lintitript

Summary for 7F8U

• Entry DOI: 10.2210/pdb7f8u/pdb
• Descriptor: Fusion protein of Cholecystokinin receptor type A and Endolysin, 2-[2-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]carbamoyl]indol-1-yl]ethanoic acid (2 entities in total)
• Functional Keywords: g protein-coulped receptor, cholecystokinin receptor cckar, lintitript, structural protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 60862.23

Authors

Zhang, X.,He, C.,Wang, M.,Zhou, Q.,Yang, D.,Zhu, Y.,Wu, B.,Zhao, Q. (deposition date: 2021-07-02, release date: 2021-10-13, Last modification date: 2023-11-29)

• Primary citation: Zhang, X.,He, C.,Wang, M.,Zhou, Q.,Yang, D.,Zhu, Y.,Feng, W.,Zhang, H.,Dai, A.,Chu, X.,Wang, J.,Yang, Z.,Jiang, Y.,Sensfuss, U.,Tan, Q.,Han, S.,Reedtz-Runge, S.,Xu, H.E.,Zhao, S.,Wang, M.W.,Wu, B.,Zhao, Q.; Structures of the human cholecystokinin receptors bound to agonists and antagonists.; Nat.Chem.Biol., 17:1230-1237, 2021; PubMed: 34556863; DOI: 10.1038/s41589-021-00866-8

Experimental method

X-RAY DIFFRACTION (2.8 Å)