7F65

Bacetrial Cocaine Esterase with mutations T172R/G173Q/V116K/S117A/A51L, bound to benzoic acid

Summary for 7F65

Entry DOI	10.2210/pdb7f65/pdb
Descriptor	Cocaine esterase, SULFATE ION, BENZOIC ACID, ... (4 entities in total)
Functional Keywords	cocaine esterase, mutantions, benzoylecgonine metabolism, hydrolase
Biological source	Rhodococcus sp. MB1 'Bresler 1999'
Total number of polymer chains	1
Total formula weight	62584.83
Authors	Ouyang, P.F.,Zhang, Y.,Tong, J. (deposition date: 2021-06-24, release date: 2021-09-15, Last modification date: 2023-11-29)
Primary citation	Chen, X.,Deng, X.,Zhang, Y.,Wu, Y.,Yang, K.,Li, Q.,Wang, J.,Yao, W.,Tong, J.,Xie, T.,Hou, S.,Yao, J. Computational Design and Crystal Structure of a Highly Efficient Benzoylecgonine Hydrolase. Angew.Chem.Int.Ed.Engl., 60:21959-21965, 2021 Cited by PubMed: 34351032 DOI: 10.1002/anie.202108559 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.202 Å)

Structure validation