7F49

von Willebrand factor (VWF) A1 domain with BT-100 aptamer RNA

Summary for 7F49

• Entry DOI: 10.2210/pdb7f49/pdb
• Descriptor: von Willebrand factor, BT-100, GLYCEROL, ... (4 entities in total)
• Functional Keywords: aptamers, arterial thrombosis, platelets, primates, von willebrand factor, blood clotting
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 34121.49

Authors

Zhu, S. (deposition date: 2021-06-18, release date: 2021-07-07, Last modification date: 2023-11-29)

• Primary citation: Zhu, S.,Gilbert, C.J.; The development and characterization of a long acting anti-thrombotic von Willebrand factor (VWF) aptamer; J Thromb Haemost., 18:1113-1123, 2020; PubMed: 32011054; DOI: 10.1111/jth.14755

Experimental method

X-RAY DIFFRACTION (2.09 Å)