7F46
Cryo-EM structure of the SARS-CoV-2 S-6P in complex with 35B5 Fab (state1, local refinement of the RBD, NTD and 35B5 Fab)
Summary for 7F46
Entry DOI | 10.2210/pdb7f46/pdb |
EMDB information | 31444 |
Descriptor | Spike glycoprotein, Heavy chain of 35B5 Fab, Light chain of 35B5 Fab, ... (4 entities in total) |
Functional Keywords | immune system, viral protein |
Biological source | Severe acute respiratory syndrome coronavirus 2 (2019-nCoV, SARS-CoV-2) More |
Total number of polymer chains | 4 |
Total formula weight | 334342.24 |
Authors | Wang, X.F.,Zhu, Y.Q. (deposition date: 2021-06-17, release date: 2022-03-23, Last modification date: 2022-09-21) |
Primary citation | Wang, X.,Hu, A.,Chen, X.,Zhang, Y.,Yu, F.,Yue, S.,Li, A.,Zhang, J.,Pan, Z.,Yang, Y.,Lin, Y.,Gao, L.,Zhou, J.,Zhao, J.,Li, F.,Shi, Y.,Huang, F.,Yang, X.,Peng, Y.,Tu, L.,Zhang, H.,Zheng, H.,He, J.,Zhang, H.,Xu, L.,Huang, Q.,Zhu, Y.,Deng, K.,Ye, L. A potent human monoclonal antibody with pan-neutralizing activities directly dislocates S trimer of SARS-CoV-2 through binding both up and down forms of RBD Signal Transduct Target Ther, 7:114-, 2022 Cited by DOI: 10.1038/s41392-022-00954-8PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.79 Å) |
Structure validation
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