7F35
Crystal structure of anti S-gatifloxacin antibody Fab fragment in complex with S-gatifloxacin
Summary for 7F35
Entry DOI | 10.2210/pdb7f35/pdb |
Related | 7F2S |
Descriptor | Antibody Fab fragment light chain, Antibody Fab fragment heavy chain, 1-cyclopropyl-6-fluoro-8-methoxy-7-[(3S)-3-methylpiperazin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid, ... (10 entities in total) |
Functional Keywords | antibody, gatifloxacin, fab fragment, enantioselectivity, immune system |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 6 |
Total formula weight | 145696.50 |
Authors | Wang, L.T.,Jiao, W.Y.,Shen, X.,Lei, H.T. (deposition date: 2021-06-15, release date: 2021-12-29, Last modification date: 2023-11-29) |
Primary citation | Wang, L.T.,Xie, W.,Jiao, W.Y.,Zhang, C.,Li, X.,Xu, Z.,Huang, X.,Lei, H.T.,Shen, X. Conformational adaptability determining antibody recognition to distomer: structure analysis of enantioselective antibody against chiral drug gatifloxacin Rsc Adv, 11:39534-39544, 2021 Cited by DOI: 10.1039/D1RA07143BPDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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