7F2W
TbUox in complex with uric acid
Summary for 7F2W
Entry DOI | 10.2210/pdb7f2w/pdb |
Descriptor | Uricase, URIC ACID (3 entities in total) |
Functional Keywords | uricase, urate oxidase, oxidoreductase |
Biological source | Thermobispora bispora (strain ATCC 19993 / DSM 43833 / CBS 139.67 / JCM 10125 / NBRC 14880 / R51) |
Total number of polymer chains | 2 |
Total formula weight | 68616.60 |
Authors | Chiu, Y.C.,Hsu, T.S.,Huang, C.Y.,Hsu, C.H. (deposition date: 2021-06-14, release date: 2022-05-04, Last modification date: 2023-11-29) |
Primary citation | Chiu, Y.C.,Hsu, T.S.,Huang, C.Y.,Hsu, C.H. Structural and biochemical insights into a hyperthermostable urate oxidase from Thermobispora bispora for hyperuricemia and gout therapy. Int.J.Biol.Macromol., 188:914-923, 2021 Cited by PubMed: 34403675DOI: 10.1016/j.ijbiomac.2021.08.081 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.16 Å) |
Structure validation
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