7EYC
Crystal structure of Tau and acetylated tau peptide antigen
Summary for 7EYC
Entry DOI | 10.2210/pdb7eyc/pdb |
Descriptor | antibody, light chain, antibody, Heavy chain, ACETYLATED TAU PEPTIDE, ... (4 entities in total) |
Functional Keywords | antibody, tau, alzheime disease, protein binding, immune system |
Biological source | Mus musculus (Mouse) More |
Total number of polymer chains | 6 |
Total formula weight | 95154.54 |
Authors | |
Primary citation | Song, H.L.,Kim, N.Y.,Park, J.,Kim, M.I.,Jeon, Y.N.,Lee, S.J.,Cho, K.,Shim, Y.L.,Lee, K.H.,Mun, Y.S.,Song, J.A.,Kim, M.S.,Pack, C.G.,Jung, M.,Jang, H.,Na, D.L.,Hong, M.,Kim, D.H.,Yoon, S.Y. Monoclonal antibody Y01 prevents tauopathy progression induced by lysine 280-acetylated tau in cell and mouse models. J.Clin.Invest., 133:-, 2023 Cited by PubMed: 36917188DOI: 10.1172/JCI156537 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.49 Å) |
Structure validation
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