7EU9
Crystal structure of the selenomethionine(SeMet)-derived Cas12i1 R-loop complex before target DNA cleavage
Summary for 7EU9
Entry DOI | 10.2210/pdb7eu9/pdb |
Related | 7D2L 7D3J 7D8C |
Descriptor | Cas12i1 D647A mutant, RNA (43-MER), DNA (31-MER), ... (6 entities in total) |
Functional Keywords | cas12i, cas12i1, crispr, rna binding protein |
Biological source | Lachnospiraceae bacterium ND2006 More |
Total number of polymer chains | 4 |
Total formula weight | 166714.57 |
Authors | Zhang, B.,Luo, D.Y.,Li, Y.,OuYang, S.Y. (deposition date: 2021-05-16, release date: 2021-05-26, Last modification date: 2021-06-23) |
Primary citation | Zhang, B.,Luo, D.,Li, Y.,Perculija, V.,Chen, J.,Lin, J.,Ye, Y.,Ouyang, S. Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1. Nat Commun, 12:3476-3476, 2021 Cited by PubMed: 34108490DOI: 10.1038/s41467-021-23876-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.35 Å) |
Structure validation
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