7EPV
Crystal structure of tigecycline degrading monooxygenase Tet(X4)
Summary for 7EPV
Entry DOI | 10.2210/pdb7epv/pdb |
Descriptor | Flavin-dependent monooxygenase, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, GLYCEROL, ... (4 entities in total) |
Functional Keywords | monooxygenase, tet(x4), tigecycline resistance, oxidoreductase |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 44407.81 |
Authors | |
Primary citation | Cheng, Q.,Cheung, Y.,Liu, C.,Xiao, Q.,Sun, B.,Zhou, J.,Chan, E.W.C.,Zhang, R.,Chen, S. Structural and mechanistic basis of the high catalytic activity of monooxygenase Tet(X4) on tigecycline. Bmc Biol., 19:262-262, 2021 Cited by PubMed: 34895224DOI: 10.1186/s12915-021-01199-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
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