7EOO

Crystal structure of the Pepper aptamer in complex with HBC525

Summary for 7EOO

• Entry DOI: 10.2210/pdb7eoo/pdb
• Descriptor: Pepper (49-MER), GUANOSINE-5'-TRIPHOSPHATE, (~{E})-2-(1,3-benzoxazol-2-yl)-3-[4-[2-hydroxyethyl(methyl)amino]phenyl]prop-2-enenitrile, ... (5 entities in total)
• Functional Keywords: fluorescent rna, aptamer, hbc525, rna
• Biological source: synthetic construct
• Total number of polymer chains: 1
• Total formula weight: 16367.92

Authors

Huang, K.Y.,Ren, A.M. (deposition date: 2021-04-22, release date: 2021-11-24, Last modification date: 2023-11-29)

• Primary citation: Huang, K.,Chen, X.,Li, C.,Song, Q.,Li, H.,Zhu, L.,Yang, Y.,Ren, A.; Structure-based investigation of fluorogenic Pepper aptamer.; Nat.Chem.Biol., 17:1289-1295, 2021; PubMed: 34725509; DOI: 10.1038/s41589-021-00884-6

Experimental method

X-RAY DIFFRACTION (2.23 Å)