7EL5

Crystal structure of Sizzled protein from Xenopus Laevis

Summary for 7EL5

Entry DOI	10.2210/pdb7el5/pdb
Descriptor	Secreted Xwnt8 inhibitor sizzled (2 entities in total)
Functional Keywords	bmp1-inhibitor, sizzled, wnt signaling, frizzled motif, signaling protein
Biological source	Xenopus laevis (African clawed frog)
Total number of polymer chains	2
Total formula weight	62958.64
Authors	Sharma, U.,Harlos, K.,Hulmes, D.J.S.,Aghajari, N. (deposition date: 2021-04-08, release date: 2022-09-14)
Primary citation	Sharma, U.,Vadon-Le Goff, S.,Harlos, K.,Zhao, Y.,Mariano, N.,Bijakowski, C.,Bourhis, J.M.,Moali, C.,Hulmes, D.J.S.,Aghajari, N. Dynamics of the secreted frizzled related protein Sizzled and potential implications for binding to bone morphogenetic protein-1 (BMP-1). Sci Rep, 12:14850-14850, 2022 Cited by PubMed: 36050373 DOI: 10.1038/s41598-022-18795-4 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation