7EGV

Acetolactate Synthase from Trichoderma harzianum with inhibitor harzianic acid

Summary for 7EGV

Entry DOI	10.2210/pdb7egv/pdb
Descriptor	Acetolactate synthase, MAGNESIUM ION, 2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]-4-METHYL-2-OXO-2,3-DIHYDRO-1,3-THIAZOL-5-YL}ETHYL TRIHYDROGEN DIPHOSPHATE, ... (10 entities in total)
Functional Keywords	acetolactate synthase, bgc, harzianic acid, transferase
Biological source	Trichoderma harzianum
Total number of polymer chains	2
Total formula weight	153526.52
Authors	Zang, X.,Xie, L.,Chen, M.,Tang, Y.,Zhou, J. (deposition date: 2021-03-26, release date: 2021-06-30, Last modification date: 2023-11-29)
Primary citation	Xie, L.,Zang, X.,Cheng, W.,Zhang, Z.,Zhou, J.,Chen, M.,Tang, Y. Harzianic Acid from Trichoderma afroharzianum Is a Natural Product Inhibitor of Acetohydroxyacid Synthase. J.Am.Chem.Soc., 2021 Cited by PubMed: 34132537 DOI: 10.1021/jacs.1c03988 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.54 Å)

Structure validation