7EGN

Crystal structure of the P450 BM3 heme domain mutant F87A in complex with N-imidazolyl-hexanoyl-L-phenylalanine and hydroxylamine

7EGN の概要

• エントリーDOI: 10.2210/pdb7egn/pdb
• 分子名称: Bifunctional cytochrome P450/NADPH--P450 reductase, PROTOPORPHYRIN IX CONTAINING FE, (2S)-2-(6-imidazol-1-ylhexanoylamino)-3-phenyl-propanoic acid, ... (6 entities in total)
• 機能のキーワード: dual-functional small molecule, p450 heme domain, complex, oxidoreductase
• 由来する生物種: Bacillus megaterium (strain ATCC 14581 / DSM 32 / JCM 2506 / NBRC 15308 / NCIMB 9376 / NCTC 10342 / VKM B-512)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 108755.43

構造登録者

Jiang, Y.,Dong, S.,Feng, Y.,Cong, Z. (登録日: 2021-03-24, 公開日: 2021-08-18, 最終更新日: 2023-11-29)

• 主引用文献: Zhang, X.,Jiang, Y.,Chen, Q.,Dong, S.,Feng, Y.,Cong, Z.,Shaik, S.,Wang, B.; H-Bonding Networks Dictate the Molecular Mechanism of H2O2 Activation by P450; Acs Catalysis, 11:8774-8785, 2021; DOI: 10.1021/acscatal.1c02068

実験手法

X-RAY DIFFRACTION (2.7 Å)