7E9Y

Crystal structure of eLACCO1

Summary for 7E9Y

Entry DOI	10.2210/pdb7e9y/pdb
Descriptor	Lactate-binding periplasmic protein TTHA0766,Lactate-binding periplasmic protein TTHA0766, CALCIUM ION, (2S)-2-HYDROXYPROPANOIC ACID, ... (4 entities in total)
Functional Keywords	biosensor, genetically encoded fluorescent biosensor, extracellular, l-lactate, fluorescent protein
Biological source	Thermus thermophilus HB8 More
Total number of polymer chains	1
Total formula weight	70188.41
Authors	Wen, Y.,Campbell, R.E.,Lemieux, M.J.,Nasu, Y. (deposition date: 2021-03-05, release date: 2021-12-22, Last modification date: 2023-11-29)
Primary citation	Nasu, Y.,Murphy-Royal, C.,Wen, Y.,Haidey, J.N.,Molina, R.S.,Aggarwal, A.,Zhang, S.,Kamijo, Y.,Paquet, M.E.,Podgorski, K.,Drobizhev, M.,Bains, J.S.,Lemieux, M.J.,Gordon, G.R.,Campbell, R.E. A genetically encoded fluorescent biosensor for extracellular L-lactate. Nat Commun, 12:7058-7058, 2021 Cited by PubMed: 34873165 DOI: 10.1038/s41467-021-27332-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation