7E7I

Cryo-EM structure of human ABCA4 in the apo state

Summary for 7E7I

• Entry DOI: 10.2210/pdb7e7i/pdb
• EMDB information: 31000
• Descriptor: Retinal-specific phospholipid-transporting ATPase ABCA4, beta-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: lipid transport, membrane protein, translocase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 266009.78

Authors

Xie, T.,Zhang, Z.K.,Gong, X. (deposition date: 2021-02-26, release date: 2021-06-30, Last modification date: 2021-07-07)

• Primary citation: Xie, T.,Zhang, Z.,Fang, Q.,Du, B.,Gong, X.; Structural basis of substrate recognition and translocation by human ABCA4.; Nat Commun, 12:3853-3853, 2021; PubMed: 34158497; DOI: 10.1038/s41467-021-24194-6

Experimental method

ELECTRON MICROSCOPY (3.3 Å)