7E6T

Structural insights into the activation of human calcium-sensing receptor

Summary for 7E6T

• Entry DOI: 10.2210/pdb7e6t/pdb
• EMDB information: 30996
• Descriptor: Extracellular calcium-sensing receptor, PHOSPHATE ION, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: g-protein-coupled receptor (gpcr); calcium-sensing receptor (casr); cryo-electron microscopy (cryo-em); calcium ions; nanobody, structural protein
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 196399.90

Authors

Geng, Y.,Chen, X.C.,Wang, L.,Cui, Q.Q.,Ding, Z.Y.,Han, L.,Kou, Y.J.,Zhang, W.Q.,Wang, H.N.,Jia, X.M.,Dai, M.,Shi, Z.Z.,Li, Y.Y.,Li, X.Y. (deposition date: 2021-02-24, release date: 2021-09-22)

• Primary citation: Chen, X.,Wang, L.,Cui, Q.,Ding, Z.,Han, L.,Kou, Y.,Zhang, W.,Wang, H.,Jia, X.,Dai, M.,Shi, Z.,Li, Y.,Li, X.,Geng, Y.; Structural insights into the activation of human calcium-sensing receptor.; Elife, 10:-, 2021; PubMed: 34467854; DOI: 10.7554/eLife.68578

Experimental method

ELECTRON MICROSCOPY (3 Å)