7E45
Crystal structure of compound 7 bound to MIF
Summary for 7E45
Entry DOI | 10.2210/pdb7e45/pdb |
Descriptor | Macrophage migration inhibitory factor, CHLORIDE ION, (2R)-7-[(2R,3R,4R,5S,6S)-6-(hydroxymethyl)-3-[(2R,3R,4R,5R,6S)-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4,5-bis(oxidanyl)oxan-2-yl]oxy-2-(4-methoxy-3-oxidanyl-phenyl)-5-oxidanyl-2,3-dihydrochromen-4-one, ... (4 entities in total) |
Functional Keywords | tautomease and cytokine, isomerase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 3 |
Total formula weight | 38136.62 |
Authors | |
Primary citation | Yang, L.,Guo, D.,Fan, C. Identification and Structure-Activity Relationships of Dietary Flavonoids as Human Macrophage Migration Inhibitory Factor (MIF) Inhibitors. J.Agric.Food Chem., 69:10138-10150, 2021 Cited by PubMed: 34459191DOI: 10.1021/acs.jafc.1c03367 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.433 Å) |
Structure validation
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