7E45

Crystal structure of compound 7 bound to MIF

7E45 の概要

• エントリーDOI: 10.2210/pdb7e45/pdb
• 分子名称: Macrophage migration inhibitory factor, CHLORIDE ION, (2R)-7-[(2R,3R,4R,5S,6S)-6-(hydroxymethyl)-3-[(2R,3R,4R,5R,6S)-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-4,5-bis(oxidanyl)oxan-2-yl]oxy-2-(4-methoxy-3-oxidanyl-phenyl)-5-oxidanyl-2,3-dihydrochromen-4-one, ... (4 entities in total)
• 機能のキーワード: tautomease and cytokine, isomerase
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 38136.62

構造登録者

Fan, C.P.,Yang, L. (登録日: 2021-02-10, 公開日: 2023-02-15, 最終更新日: 2023-11-29)

• 主引用文献: Yang, L.,Guo, D.,Fan, C.; Identification and Structure-Activity Relationships of Dietary Flavonoids as Human Macrophage Migration Inhibitory Factor (MIF) Inhibitors.; J.Agric.Food Chem., 69:10138-10150, 2021; PubMed: 34459191; DOI: 10.1021/acs.jafc.1c03367

実験手法

X-RAY DIFFRACTION (1.433 Å)