7DVB

D335N variant of Bt4394 in complex with 6SO3-NAG-oxazoline intermediate

Summary for 7DVB

• Entry DOI: 10.2210/pdb7dvb/pdb
• Descriptor: Beta-N-acetylhexosaminidase, [(3~{a}~{R},5~{R},6~{S},7~{R},7~{a}~{R})-2-methyl-6,7-bis(oxidanyl)-5,6,7,7~{a}-tetrahydro-3~{a}~{H}-pyrano[3,2-d][1,3]oxazol-1-ium-5-yl]methyl sulfate, 2-acetamido-2-deoxy-6-O-sulfo-beta-D-glucopyranose, ... (4 entities in total)
• Functional Keywords: gh20, complex, hydrolase
• Biological source: Bacteroides thetaiotaomicron
• Total number of polymer chains: 4
• Total formula weight: 248435.48

Authors

Zhang, Z.,He, Y.,Jin, Y. (deposition date: 2021-01-13, release date: 2022-01-19, Last modification date: 2023-11-29)

• Primary citation: Zhang, Z.,Dong, M.,Zallot, R.,Blackburn, G.M.,Wang, N.,Wang, C.,Chen, L.,Baumann, P.,Wu, Z.,Wang, Z.,Fan, H.,Roth, C.,Jin, Y.,He, Y.; Mechanistic and Structural Insights into the Specificity and Biological Functions of Bacterial Sulfoglycosidases; Acs Catalysis, 13:824-836, 2023; DOI: 10.1021/acscatal.2c05405

Experimental method

X-RAY DIFFRACTION (2.05 Å)