7DTU

Human Calcium-Sensing Receptor bound with L-Trp

7DTU の概要

• エントリーDOI: 10.2210/pdb7dtu/pdb
• EMDBエントリー: 30854
• 分子名称: Extracellular calcium-sensing receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, TRYPTOPHAN, ... (4 entities in total)
• 機能のキーワード: gpcr, class c, calcium sensing receptor, membrane protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 250474.96

構造登録者

Ling, S.L.,Tian, C.L.,Shi, P.,Liu, S.L.,Meng, X.Y.,Liu, L.,Sun, D.M.,Shi, C.W. (登録日: 2021-01-06, 公開日: 2021-03-10, 最終更新日: 2021-04-14)

• 主引用文献: Ling, S.,Shi, P.,Liu, S.,Meng, X.,Zhou, Y.,Sun, W.,Chang, S.,Zhang, X.,Zhang, L.,Shi, C.,Sun, D.,Liu, L.,Tian, C.; Structural mechanism of cooperative activation of the human calcium-sensing receptor by Ca 2+ ions and L-tryptophan.; Cell Res., 31:383-394, 2021; PubMed: 33603117; DOI: 10.1038/s41422-021-00474-0

実験手法

ELECTRON MICROSCOPY (4.4 Å)