7DT3

Crystal structure of human transthyretin in complex with 4-chloro-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid

7DT3 の概要

• エントリーDOI: 10.2210/pdb7dt3/pdb
• 分子名称: Transthyretin, CALCIUM ION, 4-chloranyl-9,10-bis(oxidanylidene)anthracene-2-carboxylic acid, ... (4 entities in total)
• 機能のキーワード: inhibitor, complex, t4-binding, amyloidosis, transport protein
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 35274.53

構造登録者

Kitakami, R.,Yokoyama, T.,Mizuguchi, M. (登録日: 2021-01-04, 公開日: 2021-10-13, 最終更新日: 2023-11-29)

• 主引用文献: Kitakami, R.,Inui, K.,Nakagawa, Y.,Sawai, Y.,Katayama, W.,Yokoyama, T.,Okada, T.,Kanamitsu, K.,Nakagawa, S.,Toyooka, N.,Mizuguchi, M.; Inhibitory activities of anthraquinone and xanthone derivatives against transthyretin amyloidogenesis.; Bioorg.Med.Chem., 44:116292-116292, 2021; PubMed: 34225167; DOI: 10.1016/j.bmc.2021.116292

実験手法

X-RAY DIFFRACTION (1.198 Å)