7DQQ

Crystal structure of Sulfurisphaera tokodaii O6-methylguanine methyltransferase Y91F/C120S variant in complex with O6-methyldeoxyguanosine

7DQQ の概要

• エントリーDOI: 10.2210/pdb7dqq/pdb
• 分子名称: Methylated-DNA--protein-cysteine methyltransferase, (2~{R},3~{S},5~{R})-5-(2-azanyl-6-methoxy-purin-9-yl)-2-(hydroxymethyl)oxolan-3-ol (3 entities in total)
• 機能のキーワード: methyltramsferase, transferase
• 由来する生物種: Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 18226.15

構造登録者

Kikuchi, M.,Yamauchi, T.,Iizuka, Y.,Tsunoda, M. (登録日: 2020-12-24, 公開日: 2021-12-15, 最終更新日: 2023-11-29)

• 主引用文献: Kikuchi, M.,Yamauchi, T.,Iizuka, Y.,Tsunoda, M.; Roles of the hydroxy group of tyrosine in crystal structures of Sulfurisphaera tokodaii O6-methylguanine-DNA methyltransferase.; Acta Crystallogr.,Sect.F, 77:444-451, 2021; DOI: 10.1107/S2053230X21011055

実験手法

X-RAY DIFFRACTION (2.6 Å)