7DOZ
HIV-1 Protease D30N mutant in complex with Nelfinavir
Summary for 7DOZ
| Entry DOI | 10.2210/pdb7doz/pdb |
| Descriptor | Protease, 2-[2-HYDROXY-3-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-4-PHENYL SULFANYL-BUTYL]-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID TERT-BUTYLAMIDE (3 entities in total) |
| Functional Keywords | hiv protease, viral protein |
| Biological source | Human immunodeficiency virus 1 More |
| Total number of polymer chains | 1 |
| Total formula weight | 23068.35 |
| Authors | Bihani, S.C.,Hosur, M.V. (deposition date: 2020-12-17, release date: 2021-10-27, Last modification date: 2023-11-29) |
| Primary citation | Bihani, S.C.,Gupta, G.D.,Hosur, M.V. Molecular basis for reduced cleavage activity and drug resistance in D30N HIV-1 protease. J.Biomol.Struct.Dyn., :1-9, 2021 Cited by PubMed: 34609269DOI: 10.1080/07391102.2021.1982007 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.91 Å) |
Structure validation
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