7DOZ

HIV-1 Protease D30N mutant in complex with Nelfinavir

7DOZ の概要

• エントリーDOI: 10.2210/pdb7doz/pdb
• 分子名称: Protease, 2-[2-HYDROXY-3-(3-HYDROXY-2-METHYL-BENZOYLAMINO)-4-PHENYL SULFANYL-BUTYL]-DECAHYDRO-ISOQUINOLINE-3-CARBOXYLIC ACID TERT-BUTYLAMIDE (3 entities in total)
• 機能のキーワード: hiv protease, viral protein
• 由来する生物種: Human immunodeficiency virus 1; 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 23068.35

構造登録者

Bihani, S.C.,Hosur, M.V. (登録日: 2020-12-17, 公開日: 2021-10-27, 最終更新日: 2023-11-29)

• 主引用文献: Bihani, S.C.,Gupta, G.D.,Hosur, M.V.; Molecular basis for reduced cleavage activity and drug resistance in D30N HIV-1 protease.; J.Biomol.Struct.Dyn., :1-9, 2021; PubMed: 34609269; DOI: 10.1080/07391102.2021.1982007

実験手法

X-RAY DIFFRACTION (1.91 Å)