7DOK

Structure of COVID-19 RNA-dependent RNA polymerase (extended conformation) bound to penciclovir

7DOK の概要

• エントリーDOI: 10.2210/pdb7dok/pdb
• EMDBエントリー: 30663 30664 30794 30795
• 分子名称: RNA (5'-R(P*GP*CP*UP*AP*UP*GP*UP*GP*AP*GP*AP*UP*UP*AP*AP*GP*UP*UP*AP*U)-3'), RNA (5'-R(P*CP*CP*CP*UP*AP*UP*AP*AP*CP*UP*UP*AP*AP*UP*CP*UP*CP*AP*CP*AP*UP*AP*GP*C)-3'), RNA-directed RNA polymerase, ... (10 entities in total)
• 機能のキーワード: covid-19, rna polymerase in extended conformation, penciclovir binding, viral protein
• 由来する生物種: Severe acute respiratory syndrome coronavirus 2 (2019-nCoV); 詳細
• タンパク質・核酸の鎖数: 6
• 化学式量合計: 176256.25

構造登録者

Li, Z.,Yu, X. (登録日: 2020-12-14, 公開日: 2021-12-15, 最終更新日: 2025-07-02)

• 主引用文献: Yin, W.,Luan, X.,Li, Z.,Xie, Y.,Zhou, Z.,Liu, J.,Gao, M.,Wang, X.,Zhou, F.,Wang, Q.,Wang, Q.,Shen, D.,Zhang, Y.,Tian, G.,Aisa, H.,Wei, D.,Jiang, Y.,Xiao, G.,Jiang, H.,Zhang, L.,Yu, X.,Shen, J.,Zhang, S.,Xu, H.; Structural basis for repurpose and design of nucleotide drugs for treating COVID-19; To Be Published,

実験手法

ELECTRON MICROSCOPY (2.73 Å)