7DIF

GH127 beta-L-arabinofuranosidase HypBA1 covalently complexed with beta-L-arabinofuranose-configured cyclophellitol at 1.75-angstrom resolution

7DIF の概要

• エントリーDOI: 10.2210/pdb7dif/pdb
• 分子名称: Non-reducing end beta-L-arabinofuranosidase, ZINC ION, (1S,2S,3R,4R)-3-(hydroxymethyl)cyclopentane-1,2,4-triol, ... (5 entities in total)
• 機能のキーワード: (alpha/alpha)6 barrel, glycoside hydrolase family 127, hydrolase
• 由来する生物種: Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 74710.57

構造登録者

Amaki, S.,McGregor, N.G.S.,Arakawa, T.,Yamada, C.,Borlandelli, V.,Overkleeft, H.S.,Davies, G.J.,Fushinobu, S. (登録日: 2020-11-19, 公開日: 2021-01-27, 最終更新日: 2023-11-29)

• 主引用文献: McGregor, N.G.S.,Coines, J.,Borlandelli, V.,Amaki, S.,Artola, M.,Nin-Hill, A.,Linzel, D.,Yamada, C.,Arakawa, T.,Ishiwata, A.,Ito, Y.,van der Marel, G.A.,Codee, J.D.C.,Fushinobu, S.,Overkleeft, H.S.,Rovira, C.,Davies, G.J.; Cysteine Nucleophiles in Glycosidase Catalysis: Application of a Covalent beta-l-Arabinofuranosidase Inhibitor.; Angew.Chem.Int.Ed.Engl., 60:5754-5758, 2021; PubMed: 33528085; DOI: 10.1002/anie.202013920

実験手法

X-RAY DIFFRACTION (1.75 Å)