7D9Y
DNA binding domain of human DNA Ligase IV mutant - A3V
Summary for 7D9Y
| Entry DOI | 10.2210/pdb7d9y/pdb |
| Related | 7D9K |
| Descriptor | DNA ligase 4 (2 entities in total) |
| Functional Keywords | dbd mutant a3v, native, atp dependant ligase, hypomorphic mutant, ligase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 27655.99 |
| Authors | Maddi, E.R.,Raghavan, S.C.,Natesh, R. (deposition date: 2020-10-14, release date: 2021-02-24, Last modification date: 2023-11-29) |
| Primary citation | Maddi, E.R.,Raghavan, S.C.,Natesh, R. Hypomorphic mutations in human DNA ligase IV lead to compromised DNA binding efficiency, hydrophobicity and thermal stability. Protein Eng.Des.Sel., 34:-, 2021 Cited by PubMed: 33586762DOI: 10.1093/protein/gzab001 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.76 Å) |
Structure validation
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