7D8E

Crystal Structure of double mutant Y115E Y117E human Secretory Glutaminyl Cyclase in complex with LSB-09

Summary for 7D8E

• Entry DOI: 10.2210/pdb7d8e/pdb
• Descriptor: Glutaminyl-peptide cyclotransferase, ZINC ION, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: glutaminyl-peptide cyclotransferase, sqc, alzheimer's disease, pyroglutamate, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 114817.15

Authors

Dileep, K.V.,Ihara, K.,Sakai, N.,Shirozu, M.,Zhang, K.Y.J. (deposition date: 2020-10-08, release date: 2021-12-08, Last modification date: 2023-11-29)

• Primary citation: Dileep, K.V.,Ihara, K.,Sakai, N.,Shirozu, M.,Zhang, K.Y.J.; Crystal Structure of double mutant Y115E Y117E human Secretory Glutaminyl Cyclase in complex with LSB-09; To Be Published,

Experimental method

X-RAY DIFFRACTION (2 Å)