7D30
Structure of sybody MR17-SR31 fusion in complex with the SARS-CoV-2 S Receptor Binding domain (RBD)
Summary for 7D30
Entry DOI | 10.2210/pdb7d30/pdb |
Descriptor | sybody fusion of MR17-SR31 with a GS linker, Spike protein S1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total) |
Functional Keywords | coronavirus, covid-19, nanobody, neutralizing antibody, receptor binding protein, sars-cov-2, s protein, synthetic antibody, vhh., protein binding |
Biological source | synthetic construct More |
Total number of polymer chains | 2 |
Total formula weight | 60133.98 |
Authors | |
Primary citation | Yao, H.,Cai, H.,Li, T.,Zhou, B.,Qin, W.,Lavillette, D.,Li, D. A high-affinity RBD-targeting nanobody improves fusion partner's potency against SARS-CoV-2. Plos Pathog., 17:e1009328-e1009328, 2021 Cited by PubMed: 33657135DOI: 10.1371/journal.ppat.1009328 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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