7D2K

Crystal structure of rat TRPV6 in complex with (4- phenylcyclohexyl)piperazine inhibitor Br-cis-22a

7D2K の概要

• エントリーDOI: 10.2210/pdb7d2k/pdb
• 分子名称: Transient receptor potential cation channel subfamily V member 6, CALCIUM ION, 1-(5-bromanylpyridin-3-yl)-4-[4-(3-methylphenyl)cyclohexyl]piperazin-4-ium (3 entities in total)
• 機能のキーワード: ion channels, trp channels, membrane proteins, transport protein-inhibitor complex, transport protein/inhibitor
• 由来する生物種: Rattus norvegicus (Rat)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 78004.35

構造登録者

Singh, A.K.,Neuberger, A.,Nadezhdin, K.D.,Sobolevsky, A.I. (登録日: 2020-09-16, 公開日: 2021-10-06, 最終更新日: 2023-11-29)

• 主引用文献: Bhardwaj, R.,Lindinger, S.,Neuberger, A.,Nadezhdin, K.D.,Singh, A.K.,Cunha, M.R.,Derler, I.,Gyimesi, G.,Reymond, J.L.,Hediger, M.A.,Romanin, C.,Sobolevsky, A.I.; Inactivation-mimicking block of the epithelial calcium channel TRPV6.; Sci Adv, 6:-, 2020; PubMed: 33246965; DOI: 10.1126/sciadv.abe1508

実験手法