7CW3

Cryo-EM structure of Chikungunya virus in complex with mAb CHK-263 IgG (subregion around icosahedral 2-fold vertex)

Summary for 7CW3

• Entry DOI: 10.2210/pdb7cw3/pdb
• Related: 7CVY 7CVZ 7CW0 7CW2
• EMDB information: 30476 30477 30478 30479 30480
• Descriptor: E1 glycoprotein, E2 glycoprotein, Fab heavy chain, ... (5 entities in total)
• Functional Keywords: virus, igg, localized reconstruction, virus-immune system complex, virus/immune system
• Biological source: Chikungunya virus (CHIKV); More
• Total number of polymer chains: 46
• Total formula weight: 1917210.52

Authors

Zhou, Q.F.,Fox, J.M.,Earnest, J.T.,Ng, T.S.,Kim, A.S.,Fibriansah, G.,Kostyuchenko, V.A.,Shu, B.,Diamond, M.S.,Lok, S.M. (deposition date: 2020-08-27, release date: 2020-11-04, Last modification date: 2024-03-27)

• Primary citation: Zhou, Q.F.,Fox, J.M.,Earnest, J.T.,Ng, T.S.,Kim, A.S.,Fibriansah, G.,Kostyuchenko, V.A.,Shi, J.,Shu, B.,Diamond, M.S.,Lok, S.M.; Structural basis of Chikungunya virus inhibition by monoclonal antibodies.; Proc.Natl.Acad.Sci.USA, 117:27637-27645, 2020; PubMed: 33087569; DOI: 10.1073/pnas.2008051117

Experimental method

ELECTRON MICROSCOPY (9.4 Å)