7CRQ
NSD3 bearing E1181K/T1232A dual mutation in complex with 187-bp NCP (2:1 binding mode)
Summary for 7CRQ
Entry DOI | 10.2210/pdb7crq/pdb |
Related | 7CRO 7CRP |
EMDB information | 30453 30454 30455 30456 |
Descriptor | Histone H3, Histone H4, Histone H2A, ... (9 entities in total) |
Functional Keywords | nucleosome complex, histone methyltransferase, dna, gene reguration, gene regulation |
Biological source | Xenopus laevis (African clawed frog) More |
Total number of polymer chains | 12 |
Total formula weight | 395549.52 |
Authors | |
Primary citation | Li, W.,Tian, W.,Yuan, G.,Deng, P.,Sengupta, D.,Cheng, Z.,Cao, Y.,Ren, J.,Qin, Y.,Zhou, Y.,Jia, Y.,Gozani, O.,Patel, D.J.,Wang, Z. Molecular basis of nucleosomal H3K36 methylation by NSD methyltransferases. Nature, 590:498-503, 2021 Cited by PubMed: 33361816DOI: 10.1038/s41586-020-03069-8 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.15 Å) |
Structure validation
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