7COA
Ternary complex of DNA polymerase Mu with 1-nt gapped DNA (T:dGMPNPP) and Mn
Summary for 7COA
Entry DOI | 10.2210/pdb7coa/pdb |
Descriptor | DNA-directed DNA/RNA polymerase mu, DNA (5'-D(*CP*GP*GP*CP*TP*TP*AP*CP*G)-3'), DNA (5'-D(*CP*GP*TP*A)-3'), ... (8 entities in total) |
Functional Keywords | polymerase mu, misincorporation, gap filling, mutagenesis, hydrolase, hydrolase-dna complex, hydrolase/dna |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 59565.78 |
Authors | |
Primary citation | Guo, M.,Wang, Y.,Tang, Y.,Chen, Z.,Hou, J.,Dai, J.,Wang, Y.,Wang, L.,Xu, H.,Tian, B.,Hua, Y.,Zhao, Y. Mechanism of genome instability mediated by human DNA polymerase mu misincorporation. Nat Commun, 12:3759-3759, 2021 Cited by PubMed: 34145298DOI: 10.1038/s41467-021-24096-7 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.698 Å) |
Structure validation
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