7CMJ

Crystal structure of L.donovani Hypoxanthine-guanine phosphoribosyl transferase (HGPRT)

Summary for 7CMJ

Entry DOI	10.2210/pdb7cmj/pdb
Descriptor	Hypoxanthine phosphoribosyltransferase, MAGNESIUM ION, BARIUM ION, ... (8 entities in total)
Functional Keywords	hypoxanthine, guanine, phosphoribosyl, transferase, complex, tetramer.
Biological source	Leishmania donovani (strain BPK282A1)
Total number of polymer chains	2
Total formula weight	48275.31
Authors	Parihar, P.S.,Pratap, J.V. (deposition date: 2020-07-27, release date: 2021-08-04, Last modification date: 2023-11-29)
Primary citation	Parihar, P.S.,Pratap, J.V. The L.donovani Hypoxanthine-guanine phosphoribosyl transferase (HGPRT) oligomer is distinct from the human homolog. Biochem.Biophys.Res.Commun., 532:499-504, 2020 Cited by PubMed: 32873391 DOI: 10.1016/j.bbrc.2020.08.052 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.76 Å)

Structure validation