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7CLX

Crystal structure of the DOCK8 DHR-1 domain

Summary for 7CLX
Entry DOI10.2210/pdb7clx/pdb
Related7CLY
DescriptorDedicator of cytokinesis protein 8 (2 entities in total)
Functional Keywordsguanine nucleotide exchange factor, dock, rho gtpase, cdc42, membrane, phosphoinositide, signaling protein
Biological sourceMus musculus (Mouse)
Total number of polymer chains1
Total formula weight21482.45
Authors
Kukimoto-Niino, M.,Shirouzu, M.,Yokoyama, S.,Fukui, Y.,Uruno, T. (deposition date: 2020-07-22, release date: 2021-02-10, Last modification date: 2024-03-27)
Primary citationSakurai, T.,Kukimoto-Niino, M.,Kunimura, K.,Yamane, N.,Sakata, D.,Aihara, R.,Yasuda, T.,Yokoyama, S.,Shirouzu, M.,Fukui, Y.,Uruno, T.
A conserved PI(4,5)P2-binding domain is critical for immune regulatory function of DOCK8.
Life Sci Alliance, 4:-, 2021
Cited by
PubMed: 33574036
DOI: 10.26508/lsa.202000873
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.5 Å)
Structure validation

221051

數據於2024-06-12公開中

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