7CLX

Crystal structure of the DOCK8 DHR-1 domain

Summary for 7CLX

• Entry DOI: 10.2210/pdb7clx/pdb
• Related: 7CLY
• Descriptor: Dedicator of cytokinesis protein 8 (2 entities in total)
• Functional Keywords: guanine nucleotide exchange factor, dock, rho gtpase, cdc42, membrane, phosphoinositide, signaling protein
• Biological source: Mus musculus (Mouse)
• Total number of polymer chains: 1
• Total formula weight: 21482.45

Authors

Kukimoto-Niino, M.,Shirouzu, M.,Yokoyama, S.,Fukui, Y.,Uruno, T. (deposition date: 2020-07-22, release date: 2021-02-10, Last modification date: 2024-03-27)

• Primary citation: Sakurai, T.,Kukimoto-Niino, M.,Kunimura, K.,Yamane, N.,Sakata, D.,Aihara, R.,Yasuda, T.,Yokoyama, S.,Shirouzu, M.,Fukui, Y.,Uruno, T.; A conserved PI(4,5)P2-binding domain is critical for immune regulatory function of DOCK8.; Life Sci Alliance, 4:-, 2021; PubMed: 33574036; DOI: 10.26508/lsa.202000873

Experimental method

X-RAY DIFFRACTION (1.5 Å)