7CJM

SARS CoV-2 PLpro in complex with GRL0617

Summary for 7CJM

Entry DOI	10.2210/pdb7cjm/pdb
Descriptor	Non-structural protein 3, 5-amino-2-methyl-N-[(1R)-1-naphthalen-1-ylethyl]benzamide, ZINC ION (3 entities in total)
Functional Keywords	plpro-c111s, grl0617, hydrolase
Biological source	Severe acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains	1
Total formula weight	36227.13
Authors	Fu, Z.,Huang, H. (deposition date: 2020-07-11, release date: 2020-09-02, Last modification date: 2023-11-29)
Primary citation	Fu, Z.,Huang, B.,Tang, J.,Liu, S.,Liu, M.,Ye, Y.,Liu, Z.,Xiong, Y.,Zhu, W.,Cao, D.,Li, J.,Niu, X.,Zhou, H.,Zhao, Y.J.,Zhang, G.,Huang, H. The complex structure of GRL0617 and SARS-CoV-2 PLpro reveals a hot spot for antiviral drug discovery. Nat Commun, 12:488-488, 2021 Cited by PubMed: 33473130 DOI: 10.1038/s41467-020-20718-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.2 Å)

Structure validation