7CHF

Crystal structure of the SARS-CoV-2 RBD in complex with BD-604 Fab and BD-368-2 Fab

7CHF の概要

• エントリーDOI: 10.2210/pdb7chf/pdb
• 分子名称: BD-604 Fab heavy chain, BD-604 Fab light chain, Spike protein S1, ... (5 entities in total)
• 機能のキーワード: mab, antiviral protein-immune system complex, antiviral protein/immune system
• 由来する生物種: Homo sapiens; 詳細
• タンパク質・核酸の鎖数: 5
• 化学式量合計: 120037.16

構造登録者

Xiao, J.,Zhu, Q. (登録日: 2020-07-05, 公開日: 2020-09-16, 最終更新日: 2023-11-29)

• 主引用文献: Du, S.,Cao, Y.,Zhu, Q.,Yu, P.,Qi, F.,Wang, G.,Du, X.,Bao, L.,Deng, W.,Zhu, H.,Liu, J.,Nie, J.,Zheng, Y.,Liang, H.,Liu, R.,Gong, S.,Xu, H.,Yisimayi, A.,Lv, Q.,Wang, B.,He, R.,Han, Y.,Zhao, W.,Bai, Y.,Qu, Y.,Gao, X.,Ji, C.,Wang, Q.,Gao, N.,Huang, W.,Wang, Y.,Xie, X.S.,Su, X.D.,Xiao, J.,Qin, C.; Structurally Resolved SARS-CoV-2 Antibody Shows High Efficacy in Severely Infected Hamsters and Provides a Potent Cocktail Pairing Strategy.; Cell, 183:1013-1023.e13, 2020; PubMed: 32970990; DOI: 10.1016/j.cell.2020.09.035

実験手法

X-RAY DIFFRACTION (2.674 Å)