7CEI

THE ENDONUCLEASE DOMAIN OF COLICIN E7 IN COMPLEX WITH ITS INHIBITOR IM7 PROTEIN

Summary for 7CEI

• Entry DOI: 10.2210/pdb7cei/pdb
• Descriptor: PROTEIN (COLICIN E7 IMMUNITY PROTEIN), ZINC ION, ... (4 entities in total)
• Functional Keywords: dnase, e-group colicins, protein-protein interaction, protein recognition, immune system
• Biological source: Escherichia coli str. K12 substr.; More
• Total number of polymer chains: 2
• Total formula weight: 33438.02

Authors

Ko, T.P.,Liao, C.C.,Ku, W.Y.,Chak, K.F.,Yuan, H.S. (deposition date: 1998-09-17, release date: 1999-09-17, Last modification date: 2023-09-20)

Primary citation

Ko, T.P.,Liao, C.C.,Ku, W.Y.,Chak, K.F.,Yuan, H.S.
The crystal structure of the DNase domain of colicin E7 in complex with its inhibitor Im7 protein.
Structure Fold.Des., 7:91-102, 1999

PubMed Abstract: Colicin E7 (ColE7) is one of the bacterial toxins classified as a DNase-type E-group colicin. The cytotoxic activity of a colicin in a colicin-producing cell can be counteracted by binding of the colicin to a highly specific immunity protein. This biological event is a good model system for the investigation of protein recognition.

PubMed: 10368275
DOI: 10.1016/S0969-2126(99)80012-4

Experimental method

X-RAY DIFFRACTION (2.3 Å)