7CBK

Structure of Human Neutrophil Elastase Ecotin complex

7CBK の概要

• エントリーDOI: 10.2210/pdb7cbk/pdb
• 分子名称: Ecotin, Neutrophil elastase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (8 entities in total)
• 機能のキーワード: protease-inhibitor complex, lyase
• 由来する生物種: Escherichia coli K-12; 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 95767.51

構造登録者

Jobichen, C.,Sivaraman, J. (登録日: 2020-06-12, 公開日: 2020-08-12, 最終更新日: 2023-11-29)

• 主引用文献: Jobichen, C.,Prabhakar, M.T.,Loh, S.N.,Sivaraman, J.; Structural Basis for the Inhibition Mechanism of Ecotin against Neutrophil Elastase by Targeting the Active Site and Secondary Binding Site.; Biochemistry, 59:2788-2795, 2020; PubMed: 32657577; DOI: 10.1021/acs.biochem.0c00493

実験手法

X-RAY DIFFRACTION (2.7 Å)