7C88

Complex structure of JS003 and PD-L1

Summary for 7C88

• Entry DOI: 10.2210/pdb7c88/pdb
• Descriptor: JS003 Heavy chain, JS003 Light chain, Programmed cell death 1 ligand 1, ... (4 entities in total)
• Functional Keywords: pd-l1, antibody, ph, immune system
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 6
• Total formula weight: 127349.28

Authors

Bi, X.,Shi, R.,Chai, Y.,Qi, J.,Yan, J.,Tan, S. (deposition date: 2020-05-29, release date: 2021-04-14, Last modification date: 2024-10-09)

• Primary citation: Liu, H.,Bi, X.,Zhou, Y.,Shi, R.,Yao, S.,Qi, J.,Feng, H.,Feng, M.,Yan, J.,Tan, S.; Identification of a hotspot on PD-L1 for pH-dependent binding by monoclonal antibodies for tumor therapy.; Signal Transduct Target Ther, 5:158-158, 2020; PubMed: 32839442; DOI: 10.1038/s41392-020-00254-z

Experimental method

X-RAY DIFFRACTION (1.997 Å)