7C7J
Crystal structure of SHANK3 SPN domain in complex with GTP-bound Rap1b(G12V,Q63E)
Summary for 7C7J
Entry DOI | 10.2210/pdb7c7j/pdb |
Descriptor | Ras-related protein Rap-1b, SH3 and multiple ankyrin repeat domains protein 3, GUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total) |
Functional Keywords | shank3, rap1b, spn, ras, protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 61649.91 |
Authors | Xiao, L.X.,Pan, L.F. (deposition date: 2020-05-25, release date: 2021-05-05, Last modification date: 2023-11-29) |
Primary citation | Xu, X.L.,Liu, J.P.,Wang, Y.L.,Wang, Y.,Gong, X.,Pan, L.F. Mechanistic Insights into the Interactions of Ras Subfamily GTPases with the SPN Domain of Autism-associated SHANK3. Chin.J.Chem., 38:1635-1641, 2020 Cited by DOI: 10.1002/cjoc.202000278PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.39 Å) |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)