7C6V
Crystal structure of beta-glycosides-binding protein (W177X) of ABC transporter in a closed state bound to laminaritriose (Form II)
Summary for 7C6V
Entry DOI | 10.2210/pdb7c6v/pdb |
Descriptor | Sugar ABC transporter, periplasmic sugar-binding protein, beta-D-glucopyranose-(1-3)-beta-D-glucopyranose-(1-3)-beta-D-glucopyranose, CHLORIDE ION, ... (8 entities in total) |
Functional Keywords | conformational dynamics, substrate-binding protein, induced-fit mechanism, two-step ligand binding, venus fly-trap mechanism, sugar binding protein |
Biological source | Thermus thermophilus HB8 |
Total number of polymer chains | 3 |
Total formula weight | 140191.01 |
Authors | Kanaujia, S.P.,Chandravanshi, M.,Samanta, R. (deposition date: 2020-05-22, release date: 2020-09-16, Last modification date: 2024-10-09) |
Primary citation | Chandravanshi, M.,Samanta, R.,Kanaujia, S.P. Conformational Trapping of a beta-Glucosides-Binding Protein Unveils the Selective Two-Step Ligand-Binding Mechanism of ABC Importers. J.Mol.Biol., 432:5711-5734, 2020 Cited by PubMed: 32866452DOI: 10.1016/j.jmb.2020.08.021 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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